Dihydrorhodamine 123

CAS No. 109244-58-8

Dihydrorhodamine 123( DHR 123 )

Catalog No. M23294 CAS No. 109244-58-8

Dihydrorhodamine 123 is a fluorescent probe.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Dihydrorhodamine 123
  • Note
    Research use only, not for human use.
  • Brief Description
    Dihydrorhodamine 123 is a fluorescent probe.
  • Description
    Dihydrorhodamine 123 is a fluorescent probe (λex=488 nm, λem=525 nm).
  • In Vitro
    In the presence of 10 μM Dihydrorhodamine 123 (DHR 123) the stimulation of the neutrophil NADPH oxidase by the addition of 50 nM phorbol 12-myristate 13-acetat (PMA) resultes in an increase in the rate of rhodamine generation. The fluorescent intensity of the cells, in the presence of 10 μM Dihydrorhodamine 123, increases with time following the addition of 50 nM PMA. In the presence of 10 μM Dihydrorhodamine 123, induced HL60 cells show a sustained increase in fluorescence following the addition of 50 nM PMA.
  • In Vivo
    ——
  • Synonyms
    DHR 123
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Others
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    109244-58-8
  • Formula Weight
    346.38
  • Molecular Formula
    C21H18N2O3
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO: 95 mg/mL (274.27 mM; Need ultrasonic)
  • SMILES
    O=C(OC)C1=CC=CC=C1C2C3=C(OC4=C2C=CC(N)=C4)C=C(N)C=C3
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Lydia M. Henderson et al. Dihydrorhodamine 123: a fluorescent probe for superoxide generation? Eur.J.Biochem. 217, 973-980.
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